Based on Neil Simon's hit Broadway play, 'The Odd Couple' centers on the dynamic between a pair of comically mismatched roommates. Two divorced men looking to save on rent, prim Felix (Tony Randall) rooms with gruff, sloppy Oscar (Jack Klugman), creating a situation in which the pair constantly struggles with living together in a New York City apartment. Often celebrity guest stars would appear on the series to illustrate the differences between Oscar and Felix, including publisher Hugh Hefner and Betty White.